The clinical application of biomarkers in pediatric sepsis
10.3760/cma.j.issn.1673-4912.2017.07.007
- VernacularTitle:儿童脓毒症诊断标志物的临床应用
- Author:
Lulu CAO
;
Xiaodong ZHU
- Keywords:
Sepsis;
Children;
Biomarkers
- From:
Chinese Pediatric Emergency Medicine
2017;24(7):507-511
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is still a leading cause of death in infants and children.It is the result of multiple organ dysfunction syndrome caused by infection.For sepsis,early diagnosis is very important.Biomarkers (procalcitonin,C-reactive protein,pro-inflammatory cytokines,white blood cell count,neutrophil count,left shift and CD64) during the response to infection can be used for early diagnosis.In addition,continuously monitoring these biomarkers can be used for evaluating severity of illness,monitoring of treatment responses and predicting outcome.