Research progress of MSI colorectal cancer
10.11904/j.issn.1002-3070.2017.04.017
- VernacularTitle:MSI结直肠癌的研究进展
- Author:
Yue MA
- Keywords:
MSI;
Mucinous adenocarcinoma;
PD-1;
CIMP;
BRAF
- From:
Practical Oncology Journal
2017;31(4):376-380
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the most common malignant tumors,with the improvement of living standards and eating habits of Westernization.The incidence and mortality of colorectal cancer are on the rise in China.The development of colorectal cancer is a multi-step,multi-gene involved in the process.At present,chromosome instability(CIN)and microsatellite instability(MSI)are considered to be the main genetic pathways in colorectal cancer.This article reviews research progress of MSI colorectal cancer in clinical pathology and molecular characteristics.
