Study on the efficacy and mechanism of probiotic assisted glucocorticoid on the treatment of the patients with eczema
10.3969/j.issn.1005-1678.2017.08.011
- VernacularTitle:益生菌辅助糖皮质激素对湿疹治疗的疗效及机制分析
- Author:
Zhenzhen YUAN
;
Duo ZHANG
- Keywords:
probiotics;
glucocorticoid;
eczema;
curative effect;
mechanism
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(8):27-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficacy and mechanism of probiotic assisted glucocorticoid on the treatment of the patients with eczema. Methods 92 cases with eczema from February 2015 to March 2017 were divided into two groups according to the treatment methods, the conventional group and the combined group, 46 cases in each group. The conventional group were given glucocorticoid, and the combined treatment group were received probiotics combined with glucocorticoid. The levels of serum inflammatory factors, the treatment effects of eczema and the incidence of adverse reactions were compared between the two groups before and after treatment. Results The treatment effect of eczema in combined group was higher than that in routine group (P<0.05). No severe adverse reactions occurred in the two groups. There was no significant difference in serum inflammatory factors between the two groups before treatment. The level of serum inflammatory factors in combined group was significantly better than that in tconventional group (P<0.05). Conclusion Probiotic assisted glucocorticoid is effective in the treatment of eczema. It can lower the level of inflammation and improve the condition of the body. It has no obvious adverse reaction which has the characteristics of safety and effectiveness.
