Effect of Jingangteng capsule on pelvic inflammatory disease and its influence on uterine inflammatory factors and neointima cell apoptosis
10.3969/j.issn.1005-1678.2017.08.013
- VernacularTitle:金刚藤胶囊在盆腔炎患者中的疗效观察及对子宫组织炎症因子及内膜细胞凋亡的影响研究
- Author:
Mengsi ZHANG
- Keywords:
pelvic inflammatory disease;
Jingangteng capsule;
therapeutic effect;
uterine tissue inflammation;
endometrial apoptosis
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(8):31-32
- CountryChina
- Language:Chinese
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Abstract:
Objective To observe the effect of Jingang Capsule on the inflammation and apoptosis of endometrial tissue in patients with pelvic inflammatory disease. Methods From May 2015 to August 2016 hospital admitted 60 cases of pelvic inflammatory disease, they were randomly divided into 2 groups. The control group using kangfuxiaoyan suppository treatment, observation group with Jingangteng capsule, using enzyme-linked immunosorbent assay in 2 groups before and after treatment, the levels of inflammatory factors, using immunohistochemical detection of uterine tissue FasL, Caspase-3, Caspase-8 level test, comparison of 2 groups of clinical curative effect and effect on uterine endometrial tissue inflammation and apoptosis the. Results The observation group after treatment TNF-a, IL-1 beta, IL-8 levels lower than the control group (P<0.05);the observation group after treatment, the level of IL-10, higher than that of the control group (P<0.05); the observation group after treatment FasL, Caspase-3, Caspase-8 levels higher than the control group (P<0.05). Conclusion It is ideal for the treatment of patients with pelvic inflammatory disease to be treated with Jin Teng capsule. It is worthy of popularization and application.
