The effect of combination of gliclazide and sitagliptin on the treatment of poorly obese obese patients with type 2 diabetes mellitus

VernacularTitle:心理干预联合格列齐特和西格列汀对胰岛素治疗血糖控制欠佳肥胖2型糖尿病患者的疗效
Author: Hai FU ; Haiying YING ; Qiaoli LI
Keywords: gliclazide; sitagliptin; poor glycemic control; obese type 2 diabetes mellitus
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(8):154-155
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of psychological intervention combined with gliclazide and sitagliptin on the treatment of poorly obese obese patients with type 2 diabetes mellitus. Methods 96 obese patients with type 2 diabetes mellitus who had poor control of blood glucose after insulin treatment were randomly divided into control group and experimental group,48 cases in each groups. Gliclazide and sitagliptin (FBG), glycosylated hemoglobin (HbA1c), 2h postprandial blood glucose (2hPG), fasting insulin (FIns) were measured before and after 15 weeks of treatment in the control group. situation. Results FBG, HbA1c, 2hPG and FIns were significantly lower in the experimental group than in the control group (P<0.05). Conclusion The combination of gliclazide and sitagliptin on the treatment of poorly obese type 2 diabetes mellitus with insulin treatment can significantly reduce the blood glucose level of patients and promote it.