Effect of gliclazide and sitagliptin on insulin control in poorly controlled obese patients with type 2 diabetes mellitus
10.3969/j.issn.1005-1678.2017.08.106
- VernacularTitle:格列齐特和西格列汀对胰岛素治疗血糖控制欠佳肥胖2型糖尿病患者的疗效
- Author:
Donghong TAO
;
Xiao LIU
- Keywords:
gliclazide;
Sig Leo Dean;
poor glycemic control;
obese type 2 diabetes mellitus;
curative effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(8):252-253,256
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of gliclazide and Sig Leo Dean on insulin treatment for poor glycemic control in obese patients with type 2 diabetes mellitus. Methods 80 cases of insulin treatment for poor glycemic control in obese patients with type 2 diabetes mellitus treated in our hospital from March 2015 to January 2017 were randomly divided into two groups,with 40 cases in each group.The control group was treated with gliclazide The observation group was treated with Sig Leo Dean.The therapeutic effects of the two groups were observed and compared. Results 2 hours postprandial blood glucose levels improved in the observation group was better than that of the control group, the body weight, blood pressure, fasting blood glucose of two groups were improved, and there were no significant difference between the two groups; The incidence rate of adverse reactions was 2.5% in the observation group, 10% in the control group, the difference was not statistically significant (P<0.05). Conclusion Analysis of gliclazide and Sig Leo Dean on insulin treatment for poor glycemic control in obese patients with type 2 diabetes mellitus curative effect, Sig Leo Dean for the glycaemic improvement effect is higher, reduce the incidence of adverse reactions, so more medication safety, it is worthy of clinical promotion Application.
