Observation on the short term effect of oral antibiotic at different times on the treatment of invasive periodontitis
10.3969/j.issn.1005-1678.2017.08.130
- VernacularTitle:侵袭性牙周炎基础治疗中不同时机口服抗生素的短期疗效观察
- Author:
Ci CHANG
;
Lin DU
- Keywords:
invasive periodontitis;
basic treatment;
antibiotics
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(8):306-307,311
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the short-term effect of oral antibiotic at different times on the treatment of invasive periodontitis. Methods 78 patients with invasive periodontitis from November 2015 to March 2017 were enrolled in this study. Randomized method was used to divide the patients into the observation group and the control group, 39 cases in each group. On the basis of the basic treatment, the observation group were received amoxicillin and metronidazole after oral prophylaxis, the control group were received amoxicillin and metronidazole after subgingival scaling. The plaque status before and after the basic treatment and the efficacy in the two groups after 8 weeks were compared. Results The plaque in the two groups was significantly improved after basic treatment (P<0.05). There was no significant difference in the probing depth and the loss of attachment between the two groups. The bleeding index in the observation group was significantly lower than that in the control group (P <0.05). The probing depth in the observation group was significantly better than that in the control group (P<0.05). Conclusion On the basis of basic therapy, taking antibiotics has a better therapeutic effect on the patients with invasive periodontitis. Antibiotics is use after oral prophylaxis is better than it used after subgingival scaling, which is worthy to be popularized in clinical practice.