Clinical Features of Prostate Cancer Detected on Initial and Repeated Biopsy.
- Author:
Dong Wan SOHN
1
;
Yun Seok JUNG
;
Sung Dae KIM
;
Doo Bae KIM
;
Hyun Woo KIM
;
Sae Woong KIM
;
Yong Hyun CHO
Author Information
1. Department of Urology, The Catholic University College of Medicine, Seoul, Korea. ksw1227@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Prostate cancer;
Repeated biopsy
- MeSH:
Biopsy;
Digital Rectal Examination;
Humans;
Neoplasm Grading;
Prostate;
Prostate-Specific Antigen;
Prostatic Neoplasms;
Retrospective Studies
- From:Korean Journal of Andrology
2008;26(1):35-38
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose: To determine the clinical differences between prostate cancer detected on initial biopsy and repeated biopsy Materials and Methods: Between January 2003 and December 2006, 67 patients were evaluated in this study who were diagnosed prostate cancer by transrectal ultrasound-guided biopsies and their prostate specific antigen (PSA) were below 20 ng/ml and clinical stages were less than T2. Among 67 patients, 43 patients were diagnosed at the first biopsies (group A) and others were diagnosed at the repeate biopsies (group B). We retrospectively characterized differences in clinical features such as age, digital rectal examination (DRE), prostate volume, the number of biopsy core, rate of positive core, PSA, % free PSA, Gleason score and rate of insignificant cancer. Results: There were no significant differences in age, PSA, % free PSA, rate of insignificant cancer between groups A and B. However, positive rate of DRE, prostate volume and rate of patients whose PSA were 7 ng/ml or higher in group A were significantly higher than those in group B. Despite the number of biopsy core was higher in group A, there were no differences in the number of positive biopsy core. Conclusions: Compared to the patients who were diagnosed as prostate cancer in the initial biopsies, prostate volume, positive rate of DRE and rate of Gleason score 7 or more were significantly lower in repeated biopsy group. From now on we are planning to include more patients and compare these characteristics of biopsies with the final pathological features after radical prostatectomy.
