Establishment of Clinical Use Management Mode of Adjuvant Therapy Drugs in Our Hospital
10.6039/j.issn.1001-0408.2017.25.24
- VernacularTitle:我院辅助治疗药物临床使用管理模式的建立
- Author:
Jing YANG
;
Lei ZHENG
;
Li CHEN
;
Chao SONG
- Keywords:
Adjuvant therapy drugs;
Clinical use;
Management mode;
Rational drug use;
Evidence-based medical evidence;
Off-label use
- From:
China Pharmacy
2017;28(25):3545-3548
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To standardize the clinical use of adjuvant therapy drugs. METHODS:To establish the clinical use management mode of adjuvant therapy drugs in our hospital and summarize the usage amount and irrational drug use of adjuvant therapy drugs before and after implementing the management,and the management effect was assessed. RESULTS:The manage-ment mode of adjuvant treatment drugs in our hospital included ensuring the directory for adjuvant therapy drugs,establishing the management system and ensuring its basic principles,then conducting drug use review with the ranking of drug dosages and mak-ing full use of evidence-based medical evidence,as well as developing principle of classification disposal for the irrational drug use (off-indications,overdose,ultra treatment) of adjuvant therapy drugs. After more than one year of management practice,the use of adjuvant therapy drugs in our hospital is increasingly standardized. The sales amount of adjuvant therapy drugs to all drugs was reduced from 20.90％ before management(Aug. 2014-Jul. 2015)to 15.99％(reduced by 5％)after management(Aug. 2015-Jul. 2016). Compared with Aug. 2015,the sales amount of 48 varieties in the 93 adjuvant therapy drugs was dropped more than 15％in Aug. 2016,and irrational drug use decreased obviously. CONCLUSIONS:The established management mode of adjuvant thera-py drugs in our hospital has effectively improved clinical rational drug use and reduced medical costs.
