Pros and cons of probiotics in immunocompromised individuals

VernacularTitle:益生菌在免疫缺陷人群中应用的利与弊
Author: Yanfang WU ; Xiucai FANG
Keywords: Probiotics; Acquired immunodeficiency syndrome; Neoplasms
From: Chinese Journal of General Practitioners 2017;16(9):722-725
CountryChina
Language:Chinese
Abstract: Probiotics as intestinal flora regulators are increasingly applied in clinical practice;however,the administration of probiotics in immunocompromised individuals is rarely reported.This article is aimed to review the benefits and risks of probiotics in immunocompromised individuals,such as HIV-infected individuals and patients with malignant tumors.The research evidence shows that probiotics can reduce the occurrence of different types of diarrhea,regulate the intestinal immune status and decrease the incidence of complications in immunocompromised patients.Randomized controlled clinical trials have shown that the risk of adverse events is not significantly increased in immunocompromised patients compared to those with intact immune status and the probiotics-related infections are only presented in case reports.