Efficacy of oxycodone for painless gastroscopy in pediatric patients when combined with propofol
10.3760/cma.j.issn.0254-1416.2017.07.010
- VernacularTitle:复合丙泊酚时羟考酮用于小儿无痛胃镜术的效果
- Author:
Yuxia WANG
;
Lihua JIANG
;
Tao WANG
;
Ming LEI
- Keywords:
Oxycodone;
Propofol;
Child;
Gastroscopy
- From:
Chinese Journal of Anesthesiology
2017;37(7):804-806
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of oxycodone for painless gastroscopy in pediatric patients when combined with propofol.Methods Sixty pediatric patients of either sex,aged 2-7 yr,weighing 10-28 kg,of American Society of Anesthesiologists physical status Ⅰ or Ⅱ,scheduled for elective painless gastroscopy,were divided into 2 groups (n=30 each) using a random number table:oxycodone group (O group) and sufentanil group (F group).The pediatric patients held by their parents entered the gastroscopy room,and propofol 1.5-2.0 mg/kg and penehyclidine hydrochloride 0.3 mg were intravenously injected.Oxycodone 0.1 mg/kg and sufentanil 0.1 μg/kg were intravenously injected in O and F groups,respectively.When body movement occurred during operation,additional propofol 1.0 mg/kg was intravenously injected.The occurrence of adverse reactions such as intraoperative body movement,laryngospasm and respiratory depression was recorded.The occurrence of postoperative vomiting and pain (FLACC pain scale scores ＞3) was also recorded.Results The incidence of intraoperative body movement,laryngospasm and respiratory depression and postoperative pain was significantly lower in O group than in F group (P＜0.05).Conclusion When combined with propofol,oxycodone produces better efficacy than sufentanil for painless gastroscopy in pediatric patients.
