Allergic bronchopulmonary aspergillosis associated with aspergilloma.
- Author:
Su Hee KIM
1
;
Sung Oh PARK
;
Hyuk KO
;
Wan PARK
;
Dae Sik RYU
;
Jong Wook KIM
;
Jae Gul JUNG
;
Bock Hyun JUNG
Author Information
1. Department of Internal Medicine, Asan Kangnung Hospital, University of Ulsan College of Medicine, Kangnung, Korea. jbh@knh.co.kr
- Publication Type:Case Report
- Keywords:
ABPA;
Aspergilloma;
Tuberculosis;
Pneumonectomy
- MeSH:
Adult;
Antibodies;
Aspergillosis, Allergic Bronchopulmonary*;
Aspergillus;
Asthma;
Bronchiectasis;
Colon;
Cystic Fibrosis;
Diagnosis;
Drug Resistance, Multiple;
Eosinophilia;
Follow-Up Studies;
Fungi;
Humans;
Hypersensitivity;
Immunoglobulin E;
Immunoglobulin G;
Lung;
Male;
Pneumonectomy;
Pneumothorax;
Pulmonary Aspergillosis;
Tuberculosis;
Tuberculosis, Pulmonary
- From:Korean Journal of Medicine
2002;63(1):92-97
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Aspergilloma and Allergic Bronchopulmonary Aspergillosis (ABPA) are different types of spectrum of pulmonary aspergillosis. ABPA results from hypersensitivity reaction to Aspergillus species and is known to be usually associated with bronchial asthma and cystic fibrosis. Aspergilloma results from simple colonization of this fungus within cavitary lung lesion or bronchiectasis. But rarely some patients can present together with ABPA and aspergilloma. We experienced a case of ABPA associated with aspergilloma in a 38 year-old male. The diagnosis was confirmed by asthma, immediate cutaneous reactivity to A. fumigatus, IgG antibody to A. fumigatus, elevated total and specific IgE antibodies to A. fumigatus, central bronchiectasis and peripheral eosinophilia coincident with radiographic infiltrates. During follow-up management with steroid, left pneumonectomy was done because of spontaneous pneumothorax with persistent air-leak and multidrug resistance pulmonary tuberculosis in association with aspergilloma. His respiratory symptoms and ABPA activity was much more improved after removal of aspergilloma. These findings suggest that surgical resection of aspergilloma can be considered to reduce antigenic source of colonized fungi in ABPA patients when associated with aspergilloma.
