A case of MALT lymphoma of the urinary bladder.
- Author:
Jee Yun LEE
1
;
Won Seog KIM
;
Seo Young SONG
;
Soon Il LEE
;
Joon Oh PARK
;
Ki Hyun KIM
;
Young Hyeh KO
;
Howe J REE
;
Chul Won JUNG
;
Young Hyuck IM
;
Won Ki KANG
;
Hong Ghi LEE
;
Chan Hyung PARK
;
Keun chil PARK
Author Information
1. Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center Seoul, Korea. wskimsmc@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Lymphoma;
Mucosa-Associated Lymphoid Tissue;
Bladder
- MeSH:
Cystoscopy;
Dysuria;
Female;
Gene Rearrangement;
Hematuria;
Humans;
Immunoglobulins;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone*;
Middle Aged;
Plasma Cells;
Polymerase Chain Reaction;
Prognosis;
Urinary Bladder Neoplasms;
Urinary Bladder*
- From:Korean Journal of Medicine
2002;63(1):98-102
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary lymphoma of the urinary bladder is a rare non-epithelial bladder tumor accounting for less than 1% of all bladder tumors. Approximately 17 cases of MALT lymphomas of bladder have been reported in the literature. Most reported MALT lymphomas of bladder have a female sexual preponderance with a mean age of 58 years with common presenting symptoms of hematuria, dysuria and urinary frequency. The reported prognosis of MALT lymphoma of the urinary bladder is excellent. We report a case of MALT lymphoma of urinary bladder in a 57-year-old woman patient who presented with a two-year history of persistent dysuria and urinary frequency. An intravenous pyelogram and cystoscopy revealed a 1 cm focal elevated lesion at the base of urinary bladder. The tissue obtained by transurethral resection (TUR) showed plasma cell infiltration consistent with low grade marginal zone B cell lymphoma. The immunohistochemical studies showed an immunoglobulin restriction to lambda light chain while the nested polymerase chain reaction analysis of the tissue showed a monoclonal Ig heavy-chain gene rearrangement. The clinical staging protocol revealed that the tumor was primarily arising from the urinary bladder with no evidence of other site involvements. The patient received radiation therapy of 3060 cGy in 17 fractions.
