Intraoperative parathyroid hormone detection by immunochromatography
10.3760/cma.j.issn.1674-6090.2017.04.016
- VernacularTitle:术中快速甲状旁腺激素检测在甲状腺手术中的应用研究
- Author:
Jiaqi DAI
;
Yun ZHANG
;
Jie YAN
;
Tingting WU
;
Zhiqiang YIN
- Keywords:
Thyroid surgery;
Parathyroid hormone;
Immunochromatography
- From:
Chinese Journal of Endocrine Surgery
2017;11(4):330-333
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the experience of intraoperative rapid parathyroid hormone (PTH) detection by immunochromatography in thyroid surgery.Methods Patients undergoing thyroid surgery in Shanghai Tenth People's Hospital from Nov.2016 to Jul.2017 were collected and the clinical data including level of blood calcium,serum phosphorus and PTH,and pathological findings were analyzed.Results In this study,im munochromatographic assay was used in 45 cases (experimental group) and nano carbon method was used in 47 cases (control group).In benign cases,levels of blood calcium and PTH in experimental group were higher than those in the control group ((2.07±0.09) vs (2.04±0.06) and (3.41±1.82) vs (3.34±1.84),P＞0.05).In malignant cases,blood calcium level in experimental group was higher than that in the control group ((2.02±0.13) vs (1.99±0.38),P＞0.05) and PTH level was significantly higher than that in the control group ((2.22±1.27) vs (1.44±1.44),P＜0.05).Serum phosphorus level in experimental group group was much lower than that in the control group ((1.02±0.17) vs (1.14±0.23),P＜0.05).Conclusions Using intraoperative rapid PTH detection by immunochromatography can identify parathyroid and avoid accidental injury of parathyroid gland,which can reduce the postoperative incidence of hypocalcemia.
