Effects of psychiatric nurse-led adherence therapy on clinical outcomes and medication adherence in patients with Schizophrenia: a Meta-analysis
10.3761/j.issn.0254-1769.2017.08.013
- VernacularTitle:精神科护士主导的依从性干预对精神分裂症患者临床结局影响的Meta分析
- Author:
Zhengjun WANG
;
Yuqiu ZHOU
;
Jun YANG
;
Yujing SUN
- Keywords:
Schizophrenia;
Medication Adherence;
Intervention Studies;
Meta-analysis
- From:
Chinese Journal of Nursing
2017;52(8):958-966
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the effects of psychiatric nurse-led adherence therapy on clinical outcomes and medication adherence in schizophrenia patients.Methods Searched databases to collect randomized controlled trials about psychiatric nurse-led adherence therapy for patients with schizophrenia.Two reviewers independently screened literature,extracted data,and assessed the risk of bias of included studies.Then,meta-analysis was performed using Rev Man 5.2 software.Results Fifteen studies were recruited,including 683 cases of AT and 681 cases of TAU.The results showed that adherence therapy could improve attitude towards adherence,adherence behaviors,psychotic symptoms,function,insight and reduce hospital stay.But regarding stigma,quality of life and side effects,adherence therapy did not show benefits (P＞0.05).Conclusion Psychiatric nurse-led adherence therapy is effective to improve schizophrenia patients' adherence,psychotic symptoms,function,insight and reduce hospital stay.
