Clinical observation of green laser vaporization for the treatment of bladder tumor in 522 patients
10.11958/20170420
- VernacularTitle:绿激光汽化术治疗膀胱肿瘤522例临床观察
- Author:
Zhihua ZHANG
;
Yatong CHEN
;
Zhaoyi LI
;
Tingji ZHANG
;
Qiqing FENG
;
Jian LI
- Keywords:
urinary bladder neoplasms;
recurrence;
follow up;
non muscle-invasive bladder cancer;
muscle-invasive bladder cancer;
laser therapy;
greenlight vaporization
- From:
Tianjin Medical Journal
2017;45(9):976-979
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safety and efficacy of photoselective green laser vaporization of bladder tumor (PVBT). Methods A total of 522 patients with bladder tumor were enrolled in present study from January 2010 to May 2015, including 405 cases of non muscle-invasive bladder cancer (NMIBC) and 117 cases of muscle-invasive bladder cancer (MIBC). All of patients were treated with PVBT and intravesical instillation of epirubicin. Patients with MIBC received intravenous chemotherapy (kisi-hama and cisplatin). Results The hospitalization time was (7.32±1.28) days, the operation time was (27.08±5.36) min, and the indwelling urinary catheter was (2.42±0.34) days for patients in NMIBC group. During the follow-up period (12-60 months), 38 cases (9.4％) relapsed, of which 3 cases underwent radical cystectomy, and other 35 cases underwent PVBT again. All 405 patients were alive at the end of follow-ups. The hospitalization time was(26.18 ± 1.92) days, the operation time was (38.32 ± 6.54) min, and the time of indwelling urinary catheter was (2.72 ± 0.85) days for patients of MIBC group. During the follow-up period (12-60 months), 19 cases (16.2％) relapsed. Among them, 4 patients underwent radical cystectomy, and other 15 cases underwent PVBT. Six patients died from distant organ metastasis (including 2 cases of pulmonary metastasis and 4 cases of bone metastasis), and other 111 patients survived. Conclusion PVBT is safe and effective in the clinical application, especially for NMIBC and MIBC patients who are unable or unwilling to undergo radical cystectomy.
