A new understanding of the pathogenesis of nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2017.08.037
- VernacularTitle:非酒精性脂肪性肝病发病机制新认识
- Author:
Shengliang XIN
;
Keshu XU
- Keywords:
fatty liver;
cell adhesion molecules;
vitamin D;
mental disorders;
review
- From:
Journal of Clinical Hepatology
2017;33(8):1581-1583
- CountryChina
- Language:Chinese
-
Abstract:
The incidence rate of nonalcoholic fatty liver disease (NAFLD) has been increasing in China in recent years and has reached 11％-15％.At present,the multiple-hit hypothesis is considered the main pathogenesis of NAFLD,yet the specific pathogenesis remains unknown.This article elaborates on the roles of carcinoembryonic antigen-related cell adhesion molecule 1 highly expressed in the liver,vitamin D/vitamin D receptor axis,and psychological factors in the development and progression of NAFLD,in order to provide new directions for the research on the pathogenesis of NAFLD in future.
