Analysis of related factors of diabetes foot ulcer amputation
10.3969/j.issn.1671-8348.2017.23.009
- VernacularTitle:糖尿病足溃疡患者截肢相关因素分析
- Author:
Shimin FU
;
Qingfeng CHENG
;
Shuhua DENG
;
Ying SONG
;
Mei MEI
;
Zhiping LIU
- Keywords:
diabetic foot;
ulcer;
amputation;
risk factors
- From:
Chongqing Medicine
2017;46(23):3198-3200
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore related factors of amputation in patients with diabetes foot ulcer(DFU) and provide the evidence of reducing amputation rate.Methods A total of 307 inpatients with DFU in this hospital from October 2013 to December 2015 were collected and divided into amputation group(n=28) and non-amputation group(n=279).The clinical data and laboratory data were treated with single variable analysis and multivariate Logistic regression analysis.Results Single variable analysis showed that hospitalization time,hyper-sensitive C-reactive(hs-CRP) and fibrinogen(FIB) level were significantly increased in amputation group(P＜0.05) when compared with non-amputation group,and the hemoglobin (Hb) level,high-density lipoprotein cholesterol(HDL) and serum albumin (ALB) level in amputation group were markedly lower than in non-amputation group(P＜0.05).Amputation rate was significantly different among different Wagner grades (P=0.000).Multivariate Logistic regression analysis showed that hospitalization time,Wagner grade were independent risk factors of amputation in patients with DFU,OR values were 1.024(95％CI:1.009-1.039) and 2.779 (95％CI:1.753-4.404),respectively.While HDL was a protective factor of amputation in patient with DFU (OR=0.161;95％CI:0.036-0.729).Conclusion The higher the rank of Wanger in DFU patients are,the longer hospital stay and the higher amputation risk become.HDL is the protective factor of DFU amputation.
