Progress of ameliorating the neurotoxicity of anaesthetics on developing brain
10.3969/j.issn.1672-8467.2017.04.025
- VernacularTitle:改善全麻药发育期神经毒性的研究进展
- Author:
Ying GUO
- Keywords:
general anesthetics;
developing brain;
neuroapoptosis;
cognitive impairment
- From:
Fudan University Journal of Medical Sciences
2017;44(4):532-537
- CountryChina
- Language:Chinese
-
Abstract:
General anesthetics are widely used in pregnant women,gravidas and infants.In the basic studies of rodents,mammals and non-human primate,general anesthetics can cause neurotoxicity,neuroapoptosis and damage neurodevelopment on the developing brain.Therefore,To explore protective measures and mechanism of anesthetic neurotoxicity is of great significance for formulating clinical anesthesia plan,guiding clinical obstetrics and pediatric anesthesia.This article reviewed the progress of ameliorating the neurotoxicity of general anaesthetics on developing brain including anesthetic assistants,hormone drugs,plant extracts,nutritional components and others.
