Survey and study on FYES and FYX alleles of Duffy blood group in Nanjing Han population
10.3969/j.issn.1673-4130.2017.16.011
- VernacularTitle:南京汉族人群Duffy血型等位基因FYES及FYX调查研究
- Author:
Ling MA
;
Yanchun LIU
- Keywords:
Duffy blood group;
gene frequency;
FYES;
FYX
- From:
International Journal of Laboratory Medicine
2017;38(16):2205-2206,2209
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the FYES and FYX allele expression situation of Duffy blood group in Han population of Nanjing area.Methods The genomic DNA was randomly extracted from peripheral EDTA-K2 anticoagulation blood samples in 200 voluntary blood donors and Duffy blood group FYA and FYB allele typing was performed by PCR-SSP.The EYES and FYX allele sequence charateristics of Duffy blood group were analyzed by adopting Sanger double deoxygenation gene sequencing method.Results The PCR genotyping results were consistent with the sequencing results.Among 200 samples,180 cases were FYA/FYA and 20 cases were FYA/FYB;the sequencing results showed that FYES and FYX allele expression was not been found in 200 samples.Conclusion The expression frequencies of FYES and FYX alleles are extremely low in Han population of Nanjing area,which has significant difference compared with other races.
