Analysis on correlation between lipoprotein associated phospholipase A2,D-dimer and antithrombin Ⅲ with acute cerebral infarction
10.3969/j.issn.1673-4130.2017.16.017
- VernacularTitle:脂蛋白相关磷脂酶A2、D-二聚体、抗凝血酶Ⅲ与急性脑梗死的相关性分析
- Author:
Weichuan ZHAO
;
Yingwei WU
;
Min LIU
;
Xinhong YANG
;
Zhiguo WANG
- Keywords:
acute cerebral infarction;
lipoprotein-associated phospholipase A2;
D-dimer antithrombinⅢ
- From:
International Journal of Laboratory Medicine
2017;38(16):2222-2223,2226
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the levels of lipoprotein associated phospholipase A2(Lp-PLA2),D-dimer(D-D),antithrombin Ⅲ (AT Ⅲ) in acute cerebral infarction (ACI)patients,and to analyzed their correlation with ACI.Methods Sixty-nine patients with ACI(ACI group) and 40 individuals undergoing healthy physical examination(control group) were selected in this study.The levels of Lp-PLA2,D-D and ATⅢ were compared between the two groups and their positive rates were statistically analyzed.Then the correlation between Lp-PLA2,D-D and ATⅢ with ACI was analyzed.Results The levels of Lp-PLA2 and D-D in the ACI group were higher than those in the control group,while the ATⅢ level was lower than that in the control group(P<0.05).Their positive rates in the ACI group were higher than those in the control group (P<0.05).Lp-PLA2,D-D and ATⅢ were correlated with ACI occurrence and had mutual correlation (all P<0.05).Conclusion Lp-PLA2,D-D and AT Ⅲ participate in the occurrence process of ACI,and their detection can be applied to screen out ACI high-risk groups,and may guide early prevention and early diagnosis of ACI.
