Relationship between Chlamydia trachomatis genital tract infection with detection rate of IL-2,IL-6 and serum anti-Chlamydia immunoprotein antibody
10.3969/j.issn.1673-4130.2017.16.020
- VernacularTitle:生殖道衣原体感染与IL-2、IL-6及血清抗衣原体免疫优势蛋白抗体检出率的关系
- Author:
Yun CHEN
;
Lijun HE
- Keywords:
interleukin-2;
IL-6;
anti-Chlamydia immunodominant protein antibody;
detection rate;
chlamydia
- From:
International Journal of Laboratory Medicine
2017;38(16):2229-2231
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of detection rates of IL-2,IL-6 and serum anti-Chlamydia immunodominant protein antibody in the patients with Chlamydia trachomatis genital tract infection.Methods Sixty women with genital tract infection (CT group) and 60 healthy women (control group) were selected in our hospital from January to May 2016.The serum levels of IL-2,IL-6 and anti-Chlamydia immunodominant protein and IL-2 and IL-6 levels in cervical secretions were detected in the two groups.Results The IL-2 and IL-6 levels of serum and cervical secretions in the CT group were significantly higher than those in the control group,the difference was statistically significant (P<0.05);the positive detection rates of serum OmcBc antibody,Pgp3 antibody,HSP60 antibody and CTT841 antibody in the CT group were 45.00%,75.00%,23.33% and 38.33% respectively,which were significantly higher than those in the control group,the difference was statistically significant (P<0.05).Conclusion The positive detection rates of IL-2,IL-6 and serum anti-Chlamydia immunodominant protein antibody in the patients with genital tract Chlamydia infection are significantly increased,which has some guiding significance for clinical diagnosis and treatment.
