Evaluation of T-SPOT.TB Test and Tuberculosis Antibody Detection in the Diagnosis of Tuberculosis
10.3969/j.issn.1673-4130.2017.16.022
- VernacularTitle:结核感染T细胞斑点试验及抗结核抗体检测在结核诊断中的应用价值评价
- Author:
Yu JIANG
;
Ting WU
- Keywords:
T-SPOT.TB;
serological tuberculosis antibody;
pulmonary tuberculosis;
extrapulmonary tuberculosis
- From:
International Journal of Laboratory Medicine
2017;38(16):2234-2236
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the performance of T-SPOT.TB Test and serological tuberculosis antibody(TB-Ab) in tuberculosis-assisted diagnosis.Methods Patients were diagnosed as tuberculosis from 2015 January to 2016 March in the hospital.T-SPOT.TB and tuberculosis antibody detection were performed for those patients.Results In 112 cases of tuberculosis patients,101 cases of T-SPOT.TB test were positive and the sensitivity was 90.18%,32 cases of tuberculosis antibody detection were positive and the sensitivity was 28.57%.In 41 cases of pulmonary tuberculosis,T-SPOT.TB assay showed positive results in 40 patients and the sensitivity was 97.56%,tuberculosis antibody detection showed positive results in 18 patients and the sensitivity was 43.9%;in 71 cases of extrapulmonary tuberculosis,T-SPOT.TB assay showed positive results in 61 patients and the sensitivity was 85.91%,tuberculosis antibody detection showed positive results in 14 patients and the sensitivity was 19.7%.Conclusion T-SPOT.TB was superior to serological tuberculosis antibody(TB-Ab),and the diagnosis of active tuberculosis was higher,and the sensitivity of T-SPOT.TB was higher than that of T-SPOT.TB value.
