DWI in evaluation on biological characteristics of breast invasive ductal carcinoma

VernacularTitle:DWI评价乳腺浸润性导管癌生物学特征
Author: Ruimei CHAI ; Xin WANG ; Desheng HUANG ; Yi LIU ; Lina ZHANG ; Shu LI ; Ke XU
Keywords: Breast neoplasms; Magnetic resonace imaging; Diffusion weighted imaging; Apparent diffusion coefficient
From: Chinese Journal of Medical Imaging Technology 2017;33(8):1232-1236
CountryChina
Language:Chinese
Abstract: Objective To evaluate the value of DWI in assessing the biological characteristics of breast invasive ductal carcinoma (IDC).Methods Eighty-seven IDC lesions confirmed by postoperative pathology were involved in this retrospective study.The ADC values of IDC were compared among different lymph node status,grades,and molecular subtype.The correlations of ADC value and lymph node status,grades,and molecular subtype were evaluated.Results The ADC value of IDC with positive lymph node was lower than that with negative lymph node (P=0.035),and the ADC value of the high grade IDC was lower than those of medium grade IDC and low grade IDC (P=0.021,0.002).There was no significant difference of ADC value between different molecular subtypes.There was low negative correlation of ADC value with grades (r.s =-0.357,P 0.001) and week negative correlation of ADC value lymph node status and nolecular subtype (rs =-0.227,P=0.034;rs-0.093,P＜0.001).Conclusion DWI can provide useful information in evaluating the biological characteristics of IDC.