Research progress on the pathogenesis of immune and genetics of Kawasaki disease
10.3760/cma.j.issn.2095-428X.2017.09.021
- VernacularTitle:川崎病的免疫与遗传学发病机制研究进展
- Author:
Yanqiu JIANG
;
Xianmei HUANG
- Keywords:
Kawasaki disease;
Pathogenesis;
Immunology;
Gene
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(9):717-720
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease(KD) is a childhood acute self-limiting systemic vasculitis.It is an autoimmune disease.It has replaced rheumatic fever as the most common disease of children with acquired heart disease.Further study of the pathogenesis of KD,help to improve the individualized treatment and prognosis of the disease.The current study on KD,corfirmed its susceptibility to disease and clinical symptoms associated with multiple gene loci,there may be multiple signal paths involved.This paper reviews the recent advances in the genetic and immunological mechanisms of KD.
