Biomarkers: the diagnostics and prognostics function in systemic juvenile idiopathic arthritis
10.3760/cma.j.issn.2095-428X.2017.09.003
- VernacularTitle:生物标志物:从全身型幼年特发性关节炎诊疗分型到评价体系
- Author:
Wei ZHOU
;
Jian HU
- Keywords:
Biomarker;
Systemic juvenile idiopathic arthritis;
Diagnosis;
Evaluation
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(9):648-651
- CountryChina
- Language:Chinese
-
Abstract:
Systemic juvenile idiopathic arthritis (sJIA) is a systemic inflammatory disease characterized with arthritis in one or more joints,fever,rash and serositis.Due to the atypical symptoms and poor prognosis,it's a great challenge in the clinical diagnosis and treatment efficacy evaluation in sJIA.These challenges could be addressed by the identification of clinical biomarkers,aiming at evaluating the disease severity,predicting the activity and prognosis of sJIA.This review will be focus on genetics,serum and cellular markers in sJIA and summarize the relative application on diagnosis and treatment.
