Activation mechanism and therapeutic use of microglia in subarachnoid hemorrhage

VernacularTitle:小胶质细胞在自发性蛛网膜下腔出血中的激活机制及针对其的治疗进展
Author: Shuo HAN ; Tao Lü ; Xiaohua ZHANG
Keywords: microglia; subarachnoid hemorrhage; vasospasm; activation mechanism
From: Journal of Shanghai Jiaotong University(Medical Science) 2017;37(8):1169-1173
CountryChina
Language:Chinese
Abstract: Microglia are activated and involve in the pathological and physiological processes of early brain injury and delayed cerebral ischemia after subarachnoid hemorrhage, thus impact the outcome of patients. Numerous studies have shown that microglia have different typings, signaling pathways,and functions. Interference with microglial activation or reduction of cytotoxic metabolites is important for improving the prognosis of SAH patients.