Effect of air bag on the outcome of abdominal withdrawal reflex test
10.3969.j.issn.1671-7856.2017.08.010
- VernacularTitle:气囊对腹壁撤退反射实验结果的影响
- Author:
Yan ZHAO
;
Siyuan ZHOU
;
Danni LUO
;
Ying CHEN
;
Chen HUANG
- Keywords:
Rat;
Abdominal withdrawal reflex test;
Air bag;
Standardization
- From:
Chinese Journal of Comparative Medicine
2017;27(8):50-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the preparation of air bag materials for abdominal withdrawal reflex test.Methods To measure the diameters of different pressue-air bags by digital vernier caliper and X ray imaging.Using the pain threshold (3 points) as a criterion to test the pressure values of different air bags in the rats with corresponding visceral pain sensitivity.Results With the increasing pressure, the changes of the diameter of round latex balloon were uniform and gentle, and could meet the pressure range used in the experiment (20~80 mmHg).The threshold of visceral pain in rats was near the nociceptive stimulus value,and would not cause irreversible damage to the rat intestinal tract.Conclusions Air bag made from round latrex ballon is an ideal tool to be used in abdominal withdrawal reflex test in rats.
