Content Comparison of Total Saponins and Total Polysaccharides between Formula Granules and Traditional Decoction of Sijunzi Decoction
- VernacularTitle:四君子汤配方颗粒与传统汤剂中总皂苷和总多糖含量比较
- Author:
Yuancan LIN
;
Haiying LUO
;
Qianxing JIN
- Keywords:
Sijunzi decoction;
Formula granule;
Traditional decoction;
Total saponins;
Total polysaccharides;
Content
- From:
China Pharmacist
2017;20(5):798-801
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare the content of total saponins and total polysaccharides between formula granule and traditional decoction of Sijunzi decoction.Methods: UV spectrophotometry was used to determine the content of total saponins and total polysaccharides in formula granule and traditional decoction of Sijunzi decoction respectively at the wavelength of 540 nm and 488 nm.Results: The absorbance of ginsenoside Re had a good linear correlation with the concentration within the range of 10.909-65.454 μg · ml-1 (r=0.999 7), and the average recovery was 98.49%(RSD=0.85%, n=6);the absorbance of D-anhydrous glucose had a good linear correlation with the concentration within the range of 2.160-12.960 μg · ml-1 (r=0.999 7), and the average recovery was 99.46%(RSD=0.73%, n=6).The contents of total saponins from 3 batches of formula granule were slightly higher than those from traditional decoction,and that of total polysaccharides in formula granule was slightly lower than that in traditional decoction,and there was no significant difference between the two groups (P>0.05)Conclusion: The difference of material basis between formula granule and traditional decoction of Sijunzi decoction is small, and formula granule is more feasible for clinical application.
