In vitro Antilipid-peroxidation Effects of Tannins Extract from Sanguisorba Officinalis on Heart, Liver, Brain and Kidney of Rats
- VernacularTitle:地榆鞣质提取物对大鼠心、肝、脑及肾组织体外抗脂质过氧化作用的研究
- Author:
Peng CHEN
;
Jing WANG
;
Hongpan ZHANG
;
Yue WU
;
Benhong ZHOU
- Keywords:
Sanguisorba officinalis L.;
Tannins;
Lipid peroxidation;
Malondialdehyde;
Free radicals
- From:
China Pharmacist
2017;20(5):824-827
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the in vitro antilipid-peroxidation effects of tannins extract from Sanguisorba officinalis on heart, liver, brain and kidney of rats.Methods: The in vitro inhibitory effects of tannins extract from Sanguisorba officinalis on lipid-peroxidation of heart, liver, brain and kidney of rats induced by Fe2+-cysteine (Fe2+-Cys), Fe2+-vitamin C (Fe2+-Vit C) and Fe2+-H2O2 were determined by spectrophotometry.Results: The inhibitory effects of tannins extract from Sanguisorba officinalis on MDA produced by lipid-peroxidation of brain, heart, liver homogenate, kidney and mitochondria of rats induced by Fe2+-Cys, Fe2+-Vit C and Fe2+-H2O2 were all significant.Conclusion: Tannins from Sanguisorba officinalis has good in vitro protective effects on antilipid-peroxidation of heart, liver, brain and kidney of rats, which is worth studying further.
