Safety and efficacy of transurethral Thulium laser resection of high-risk stage bladder tumor in anticoagulant state
10.3760/cma.j.issn.0254-9026.2017.05.021
- VernacularTitle:铥激光经尿道膀胱肿瘤切除术治疗抗凝状态下高龄高危膀胱肿瘤患者的安全性与疗效
- Author:
Baochun CHEN
;
Kewei ZHANG
;
Longjiang TIAN
;
Lifeng LIU
;
Qingfeng SUN
;
Feng SUN
;
Yuzhang QU
;
Hao WANG
;
Wenxiang JIN
- Keywords:
Lasers;
Urinary bladder neoplasms
- From:
Chinese Journal of Geriatrics
2017;36(5):560-562
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study safety and efficacy of transurethral Thulium laser resection of high-risk stage bladder tumor in anticoagulant state.Methods A total of 26 non-muscle invasive bladder cancer patients receiving long-term anticoagulant therapy,including 16 cases with cerebral infarction,7 cases with coronary heart disease,3 patients with coronary stenting,were retrospectively analyzed in our hospital from July 2012 to July 2014.In condition not stopping anticoagulants,Thulium laser transurethral resection of bladder tumor was performed,and hemoglobin,thrombin time,the operative time,intraoperative blood loss,postoperative bladder irrigation duration,postoperative hospital stay,bladder tumor recurrence within two years,the postoperative complications were recorded before and after surgery.Results All patients were successfully treated.The operative time was(29.1 ± 12.8) min,int raoperative blood loss was (29.4 ± 16.9) ml portions,postoperative bladder irrigation time was (1.25 ± 0.55) d,postoperative hospital stay was(5.51 ± 1.06) d.Hemoglobin before and after operation were (131.35 ± 6.57) g/L and (129.75 ± 11.05) g/L respectively,there was no statistically significant differences (t =1.014,P > 0.05) between them.Prothrombin time before and after operation were (12.50 ± 0.25) s and(12.44 ± 0.27) s,with no statistically significant difference (t =0.908,P>0.05)between them.During the followed-up of 48 months,tumor recurred at heterotopia in 2 patients.Conclusions Thulium laser transurethral resection of bladder tumor is safe and effective for patients undergoing long-term oral anticoagulation drugs,without a needto stop taking anticoagulant drugs.