Effect of botulinum toxin A combined with delivery autologous platelet rich plasma into skin with microneedle for facial rejuvenation
10.3969/j.issn.1005-6483.2017.05.019
- VernacularTitle:A型肉毒素联合微针导入自体富血小板血浆对面部年轻化患者临床疗效、皮肤指标及生活质量的影响
- Author:
Jin ZENG
;
Daixiong TIAN
- Keywords:
botulinum toxin A;
microneedle;
autologous platelet rich plasma;
facial rejuvenation
- From:
Journal of Clinical Surgery
2017;25(5):382-385
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of botulinum toxin A combined with delivery autologous platelet rich plasma into skin with microneedle for facial rejuvenation.Methods 82 patients from our hospital treated for facial rejuvenation were randomly divided into observation group(41 cases)and control group(41 cases).The control group was given delivery autologous platelet rich plasma into skin with microneedle therapy.The observation group was treated with botulinum toxin A on the base of control group.After the treatment,the effect was observed.The facial skin moisture,skin elasticity,grease and spots were detected before and after treatment in the two groups.Before and after treatment,the role function,emotional function,social function,body function and the overall quality of life score were detected by the quality of life table.Observe all of the patients reaction duration of therapy.Results The total effective rate was 95.1% in observation group,significantly higher than the control group(P<0.05).After the treatment,the facial skin moisture and skin elasticity scores were(51.24±8.31)and(62.73±8.59)in observation group,significantly higher than the control group(P<0.05),while the grease and spots scores were(41.87±7.47)and(42.13±7.62)in observation group,significantly lower than the control group(P<0.05).After the treatment,the role function,emotional function,social function and the overall quality of life score were(71.08±8.75),(66.21±7.04),(81.80±13.42)and(75.18±7.97)in observation group,significantly higher than the control group(P<0.05),while the body function score was similar in the two groups(P>0.05).And there was no adverse reactions happened in the two groups.Conclusion Botulinum toxin A combined with delivery autologous platelet rich plasma into skin with microneedle for facial rejuvenation has a good effect and high safety.
