Roles of autophagy in cardiovascular diseases:research progression
10.3760/cma.j.issn.0254-9026.2017.05.027
- VernacularTitle:自噬在心血管疾病中作用的研究进展
- Author:
Ling DU
;
Qing HE
- Keywords:
Cardiovascular diseases;
Autophagy
- From:
Chinese Journal of Geriatrics
2017;36(5):589-593
- CountryChina
- Language:Chinese
-
Abstract:
The morbidity and mortality of cardiovascular diseases(CVD)are still high in our country,they severely threaten peopleS health and quality of life.A dysregulated or reduced autophagy is associated with ischemic heart disease,cardiac hypertrophy,heart failure and arrhythmia.Autophagy is a key regulator in CVD development,and is essential for maintenance of heart function and improvement of prognosis.Thus,modulating autophagy represents an attractive future therapeutic target for treating cardiovascular disease.This article reviewed the research progression about effects of autophagy on ischemic heart disease,cardiac hypertrophy,heart failure and arrhythmia.
