Construction of Essential Medicine Selection Model Based on Knapsack Theory
10.6039/j.issn.1001-0408.2017.15.01
- VernacularTitle:基于背包理论的基本药物遴选模型构建
- Author:
Zhe HUANG
;
Yang CAO
;
Hui LI
- Keywords:
Knapsack theory;
Essential medicine;
Selection model;
Empirical study;
Rational use of medicines
- From:
China Pharmacy
2017;28(15):2017-2020
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide reference for replenishing and perfecting essential medicine selection method in China. METHODS:According to the requirements of essential medicine selection,based on the actual situation,target function and restraint conditions for essential medicine selection could be determined by the knapsack theory and the essential medicine selection model could be built. The feasibility of established model was analyzed by an sample. RESULTS:The objective function of estab-lished model was Min∑CjXj,the minimum cost of all the selected essential medicines. Other constraints included covered range of disease,ADR,contraindications,attentions,dosage forms and specifications. Nine kinds of common oral hypoglycemic drugs were selected as candidate drugs,from which glipizide,gliclazide,metformin and repaglinide were chosen as the essential hypogly-cemic medicines with the proposed model. CONCLUSIONS:Established essential medicine selection model based on knapsack the-ory is scientifical,objective and with strong practicality.
