Effects of Camellia sinensis Leaf Extract on Dental Caries Causing Streptococcus mutans
- Author:
Nguyen Thi Ngoc Dao
- Publication Type:Journal Article
- Keywords:
Dental Caries, Streptococcus mutans, treatment
- MeSH:
Tea;
Plants;
Biochemistry;
Dental Caries;
Streptococcus mutans
- From:Journal of Medicinal Materials - Hanoi
2003;8(4):110-114
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Previous papers have reported that polyphenols from green tea (Camelia sinensis L.) were useful for controlling dental caries. This study examined the effects of the ethanol total polyphenol extract (CX) of green tea leaves on dental caries causing Streptococcus mutans. CX showed to inhibit the glycolysis, biofilm formation and respiration of S. mutans. At the concentration of 0.05%, CX suppressed 30% oxygen consumption in glucose excessive medium, totally inhibited NADH oxidase activity and killed the bacteria with D value of about 13 minutes. The combination of 0.025% CX and 0.25 mM NaF blocked pH drop during glycolysis. Polyphenols from green tea leaves inhibited therefore the adherence of S. mutans in vitro and proved to be effective against dental caries.
