Treatment strategy of complete response cases after neoadjuvant radiotherapy in rec-tal cancer
10.3969/j.issn.1000-8179.2017.09.282
- VernacularTitle:直肠癌术前放化疗完全缓解后的临床策略分析
- Author:
Quanying LI
;
Bingyu DU
;
Changjiang QIN
;
Guoxiao GUO
;
Xuequn REN
- Keywords:
rectal neoplasms;
neoadjuvant chemoradiation therapy;
complete response
- From:
Chinese Journal of Clinical Oncology
2017;44(9):434-436
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss treatment of complete response cases after neoadjuvant radiotherapy in rectal cancer. Methods:This retrospective study analyzed clinical data of 84 rectal cancer cases with pre-operative neoadjuvant chemoradiotherapy in our hospital from January 2010 to Augnst 2014. Results:After neoadjuvant chemoradiotherapy, 33 patients presented clinically complete response at a rate of 39.3%. After post-operative pathologic examination, among clinically complete response cases, six cases exhibited patho-logically complete responses at a rate of 18.2%. No recurrence or disease progression occurred within 12-36 months of post-operative follow up. Conclusion:Neoadjuvant chemoradiotherapy can significantly lower tumor stage and promote clinically complete remission of some patients. However, for clinically complete remission cases, further radical surgery should be provided.
