Analysis of magnetic susceptibility of normal brain of young adults by quantitative susceptibility mapping
10.13929/j.1003-3289.201609149
- VernacularTitle:基于定量磁敏感成像的正常青年人脑磁化率分析
- Author:
Julu HONG
;
Xiaoming SHEN
;
Ruiliang LU
;
Hai ZHAO
;
Xiaohong HE
;
Xinhan ZHOU
;
Mingyong GAO
- Keywords:
Quantitative susceptibility mapping;
Magnetic resonance imaging;
Magnetic susceptibility;
Iron;
Brain
- From:
Chinese Journal of Medical Imaging Technology
2017;33(5):693-697
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of susceptibility of different sides and gender in healthy young adults with quantitative susceptibility mapping (QSM).Methods Totally 41 healthy young right-handed adults underwent conventional brain MRI and QSM scan,and the susceptibility maps were obtained by the image post-processing software.Then the ROI of the bilateral frontal grey matter (FGM),frontal white matter (FWM),caudate (CA),globus pallidus (GP),putamen (PU),thalamus (TH),substantia nigra (SN),red nucleus (RN),dentate nucleus (DN),pons (PO),corpus callosum (CC) were manually drawn to obtain magnetic susceptibility on the susceptibility map.The magnetic susceptibility of each ROI was compare between both sides,as well as gender by Mann-Whitney test.Results The magnetic susceptibility of the bilateral ROI of GP was the highest,and SN was followed,FWM was minimum.The susceptibility of bilateral FGM,FWM,CA,GP,PU,TH,SN,RN,DN,PO,CC had no statistically significant differences (all P＞0.05).The magnetic susceptibility in CA of different gender had statistically significant difference (P＜0.05).Conclusion The brain magnetic susceptibility.can be measured by QSM,and it can assess brain iron content quantitatively.
