Isolation of Flavonoids from Excoecaria cochinchinensis Lour. var. cochinchinensis
- Author:
Nguyen Thi An
- Publication Type:Journal Article
- Keywords:
flavonoid, isolation, Excoecaria cochinchinensis Lour. var. cochinchinensis
- MeSH:
Plants;
Medicine, Traditional;
Biochemistry;
Flavonoids
- From:Journal of Medicinal Materials - Hanoi
2003;8(4):103-107
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The remedy Excoecaria cochinchinensis Lour. var. cochinchinensis (Euphorbiaceae) has been commonly used in folk medicine for the treatment of itches, furuncles, allergies. Previous reports have examined the chemical composition of the leaves, two compounds have been isolated and identified as gallic acid (FAD1) and ellagic acid (FAD 2). This study was carried out for the isolation and identification of the other chemical constituents. The leaves of E. cochinchinensis Lour. var. cochinchinensis were collected at Ha Noi city and Thai Binh province. The ethyl acetate extract of the leaves were successively chromatographed on silica gel G 60 and Sephadex LH-20 columns to afford two compounds named FAD 7 and FAD 8. The spectral analysis performed on EIMS, 1H-NMR and 13C-NMR has identified FAD7 as kaempferol 7-0-glycoside, and FAD 8 as kaempferol. These two flavonols were isolated from the leaves of the plant for the first time.
