Correlation of CEUS and microvessel density in inverted papilloma of bladder and bladder urothelial carcinoma
10.13929/j.1003-3289.201609111
- VernacularTitle:膀胱内翻性乳头状瘤和膀胱尿路上皮癌CEUS与微血管密度的相关性
- Author:
Suping GUO
;
Aiyun ZHOU
;
Pan XU
;
Fan XIAO
- Keywords:
Papilloma,inverted;
Bladder urothelial carcinoma;
Microvessel density;
Contrast media;
Ultrasonography
- From:Chinese Journal of Medical Imaging Technology
2017;33(5):756-759
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between time-intensity curve (TIC) parameters of CEUS and microvessel density (MVD) of inverted papilloma of bladder (IPB) and bladder urothelial carcinoma (BUC).Methods Clinical and CEUS characteristics of 30 patients with IPB and 50 patients with BUC confirmed by pathology were retrospectively analyzed.CEUS TIC parameters included rise time (RT),mean transit time (MTT),peak intensiy (PI),time from peak to one half (TPH),wash in slope (WIS),time to peak (TP),semi-descending slope (DS) were acquired by QLab software and statistical analysis was carried out.The MVD of the resectioned tissue specimens were quantified via immunohistochemistry for CD34 and the correlation with CEUS TIC parameters was investigated.Results In CEUS quantitative parameters,PI,TPH,TP and DS had statistical significance in IPB and BUC (all P＜＜0.05).MVD of BUC was obviously higher than that of IPB (P＜0.05);TPH and DS both correlated with MVD (rs =0.74,-0.81,both P＜0.05).Conclu sion CEUS characteristics has certain clinical value in identification of IPB and BUC.TIC parameters of CEUS can reflect the MVD of IPB and BUC.
