Clinical study on nutriti0nal interventi0n in patients with Alzheimer(s) disease

VernacularTitle:口服肠内营养液改善阿尔茨海默病病人的临床研究
Author: Peng LI ; Ping LIN
Keywords: Alzheimer disease; Nutritional intervention; Oral nutritional supplements
From: Parenteral & Enteral Nutrition 2017;24(2):75-77
CountryChina
Language:Chinese
Abstract: Objective:To explore the effects of nutritional intervention on the nutritional status,cognitive function and activities of daily living (ADL) in patients with Alzheimer's Disease (AD).Methods:90 AD patients were randomly divided into the control group and the intervention group,with 45 cases in each group.Patients in the control group received anti-dementia drugs,and patients in the intervention group additionally received TPF-T as the oral nutritional supplement.The nutritional status and nutritional biochemical indicators,cognitive function and ADL of two groups were evaluated when enrolled and 6 months later after the treatment.Results:After 6 months'treatment,the nutritional status,MMSE,ADL scores and nutritional indicators of patients in the intervention group were significantly improved compared to the control group (P ＜ 0.05).Conclusion:Nutritional intervention can effectively improve the nutritional status,cognitive function and ADL of patients with dementia.