Pharmaceutical Care on an H Hypertension Case with MTHFR Gene Mutation
10.3870/j.issn.1004-0781.2017.04.011
- VernacularTitle:H型高血压伴MTHFR基因突变的药学监护
- Author:
Xiaochun YE
;
Yong HAN
;
Feng ZHU
;
Yihui LIU
;
Geng ZHANG
- Keywords:
MTHFR gene type;
Hypertension,H;
MTHFR gene polymorphism;
Pharmaceutical care
- From:
Herald of Medicine
2017;36(4):403-405
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of clinical pharmacist in individualized treatment of hypertension.Methods A patient withH hypertension receiving pharmaceutical care from clinical pharmacists was retrospectively analyzed.Results Patient's MTHFR (C677T) gene type was TT homozygous.Clinical pharmacist suggested doctor modify treatment,and then patient's plasma homocysteine dropped from 61.5 to 16.0 μmol·L-1,and blood pressure dropped from 173/ 111 mmHg(1 mmHg =0.133 kPa) to 130/80 mmHg.Conclusion Clinical pharmacist provides individualized treatment for patient with hypertension to ensure the safety and effectiveness of the drug by genotyping.
