Simultaneous pancreas-kidney transplantations for type 2 diabetes mellitus with end stage renal disease-73 cases report

VernacularTitle:2型糖尿病合并终末期肾病行胰肾联合移植73例的临床分析
Author: Yingxin FU ; Wenli SONG ; Chunbai MO ; Gang FENG ; Zhongyang SHEN
Keywords: Type 2 Diabetes mellitus; Type 1 Diabetes mellitus; Simultaneous pancreas-kidney transplantation; Pancreas transplantation; Insulin
From: Chinese Journal of Organ Transplantation 2017;38(1):1-5
CountryChina
Language:Chinese
Abstract: Objective To explore the indications of simultaneous pancreas-kidney (SPK) transplantation for type 2 diabetes mellitus (DM) combined with end-stage renal disease by comparing the outcome of patients with type 1 and type 2 DM combined with end-stage renal disease after renal transplantation.Methods 109 patients accepting SPK from January 2008 to July 2016 in our center were divided into two groups according to the types of DM:T1DM (n =36),and T2DM (n =73).The basic characteristics of recipients,outcome,and pancreas and kidney functions after operation were compared between two groups.Results There was no significant difference in 5-year survival rate and surgical complications between two groups although recipients of T2DM group were older and had higher BMI than T1DM group.But rejection rate was higher in T1DM group.Conclusion SPK for T2DM recipients will not increase the surgical risk and can get good long-term outcome.