A Case of Linear IgA Bullous Dermatosis.
- Author:
Sang Won JEONG
;
Sang Won LEE
;
Seung Hoon CHA
;
Seok Don PARK
- Publication Type:Case Report
- MeSH:
Adolescent;
Blister;
Dapsone;
Humans;
Immunoglobulin A;
Immunoglobulin G;
Linear IgA Bullous Dermatosis*;
Male;
Neutrophils;
Skin;
Transcutaneous Electric Nerve Stimulation
- From:Korean Journal of Dermatology
1998;36(5):962-964
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We describe an 18-year-old male with generalized pruritic, tense annular or polycyalic blistera on normal-appearing skin or erythematous bases. Histopathological fmdings of an iatact early blistering showed subepidermal blistering and papillary neutrophilic gnicroabscesses. A direct immunofluctescent study of a section from the skin adjacent to a lesioti revealed linear deposits of IgA at the dermoepidermal junction. There were no deposits of IgG, lgM, or C3. In 1.0M NaC1 eplit skin, IgA was found to be bound linearly on the epidermal roof. The patient respmded weIl to eteroid and dapsone therapy.