Clinical trial of Supplemented Xijiao Powder treating HBV associated prior acute-on-chronic liver failure

VernacularTitle:犀角散加味干预HBV相关慢加急性肝衰竭的前期临床研究
Author: Yanyao YIN ; Yunhua LIN ; Fazhu SHAO ; Huimin LIN ; Yali ZONG ; Yong WAN
Keywords: Supplemented Xijiao Powder; hepatitis B virus (HBV); acute-on-chronic liver failure; clinical research
From: Chinese Traditional Patent Medicine 2017;39(8):1591-1594
CountryChina
Language:Chinese
Abstract: AIM To observe the clinical role for Supplemented Xijiao Powder (Bubali cornu,Coptidis Rhizoma,Cimicifugae Rhizoma,etc.) in management of hepatitis B virus (HBV) associated acute-on-chronic liver failure.METHOD Seventy-five patients,including the ones receiving internal medicine treatment,were divided into control group and experimental group.The experimental group received conventional treatment and additionally took Supplemented Xijiao Powder for one month.The clinical symptoms and signs were observed.Levels of ALT,AST,TBIL,ALB,CHE,PTA were measured,and the incidence of liver failure was evaluated.RESULTS Supplemented Xijiao Powder could improve symptoms,signs and the level of PTA.The incidence of liver failure tended to reduce.The comparison of other indexes had no marked difference.CONCLUSION Supplemented Xijiao Powder has a certain therapeutic effect on HBV associated prioracute-on-chronic liver failure.Its mechanism may be related to blocking the occurrence of liver failure.