Progresses of TGF-β-Smad signaling pathways and epithelial-mesenchymal transition in stented blood vessel stenosis
10.13929/j.1672-8475.201609002
- VernacularTitle:TGF-β—Smad信号通路和上皮细胞-间充质转化在支架后血管狭窄中的研究进展
- Author:
Yifan WU
;
Fuquan LIU
- Keywords:
Stents;
Stenosis;
TGF-β-Smad protein signal;
Epithelial-mesenchymal transition
- From:
Chinese Journal of Interventional Imaging and Therapy
2017;14(3):182-185
- CountryChina
- Language:Chinese
-
Abstract:
There is a high risk of re-stenosis after implanting blood vessels stent,the processes involves the transforming growth factor-β (TGF-β)-Smad signaling pathways,epithelial-mesenchymal transition (EMT) and so on.The function of TGF-β-Smad signal pathways and EMT in vascular stent re-stenosis and the relevant mechanism were reviewed in this paper.