CT-guided radioactive 125I seeds implantation in treatment of spinal metastatic tumors
10.13929/j.1672-8475.201605014
- VernacularTitle:CT引导下经皮穿刺125I粒子植入治疗脊柱转移瘤
- Author:
Zhijin CHEN
;
Jian LU
;
Liyun ZHANG
;
Ju GONG
;
Ning XIA
;
Zhongmin WANG
- Keywords:
Spine;
Neoplasm metastasis;
Tomography,X-ray computed;
Iodine isotopes;
Radiotherapy
- From:
Chinese Journal of Interventional Imaging and Therapy
2017;14(3):139-142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluated the safety and clinical efficacy of CT-guided percutaneous radioactive 125I seeds implantation in treatment of spinal metastatic tumors.Methods Totally 20 cases (23 lesions) of spinal metastatic tumors with spinal compression and severe back pain were treated by CT-guided percutaneous 125I seeds implantation.Intractable pain and nerve function before and after therapy were evaluated.And the postoperative cumulative local tumors control rates and cumulative survival rates were calculated.Results The median follow-up period was 14 months (range 7-32months).There was no patient lost follow-up.And no severe complication occurred.Intractable pain significantly relieved one month after therapy.The neural retention rate of 12 patients with nerve function impairment was 85.00％ (17/20) and the neural function recovery rate was 30.00％ (6/20) three months after 125 I seeds'implantation.The local tumors control rates in 3-,6-,and 12-month were 100％,100％ and 90％,respectively.The survival rates in 6-and 12-month was 100％and 78.81％,respectively.Conclusion CT-guided percutaneous radioactive 125I seeds implantation for spinal metastatic tumors is safe and feasible.It can relief pain and improve neural function effectively.
