Assessment of two methods in evaluating alveolar bone loss by micro-CT based on periodontitis model in mice
10.13929/j.1672-8475.201607059
- VernacularTitle:两种利用micro-CT测量小鼠牙周炎模型牙槽骨吸收的方法比较
- Author:
Di CUI
;
Yangheng ZHANG
;
Ting ZHANG
;
Tingli WEI
;
Fuhua YAN
- Keywords:
Alveolar bone loss;
Periodontitis;
Tomography,X-ray computed
- From:
Chinese Journal of Interventional Imaging and Therapy
2017;14(3):173-177
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate two methods measuring alveolar bone loss by micro computed tomography (micro-CT)based on periodontitis model in mice.Methods The silk ligatures were tied around the right maxillary second molars of mice to induce periodontitis model.The right half maxillaries of mice model were harvested for micro-CT analysis.Three dentists were recruited for the measurement with two different methods:Modified tomography (T) method and reconstruction (R) method.Accuracy and consistency of each method were estimated by standard deviation (SD).Results The SDs of R method managed by the same operator (measurement for 3 times) or different operators (3 operators) were 34.87μm and 35.67 μm respectively,while that of T method was 7.82 μm and 14.24 μm respectively.The SDs of T method were significantly lower than those of R method (both P＜0.05).Conclusion T method is more accurate and consistent than R method for evaluating alveolar bone loss in mice periodontitis model.
