Effect of compatibility of pethidine hydrochloride and anisodamine on the patients with advanced malignant obstructive jaundice in PTBS operation
10.3969/j.issn.1002-1671.2017.06.025
- VernacularTitle:盐酸哌替啶联合山莨菪碱在梗阻性黄疸介入干预术中的应用
- Author:
Hongxia LI
;
Dianjing SUN
;
Yu GONG
;
Haihua LIU
;
Yanjun LIU
- Keywords:
pathidine hydrochloride;
anisodamine;
drug combination;
advanced malignant obstructive jaundice;
PTCD;
PTBS
- From:
Journal of Practical Radiology
2017;33(6):611-613,628
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of the combination of pathidine hydrochloride and anisodamine on the intraoperative effiacy of transhepatic biliary drainage and stent implantation done on the patient with advanced malignant obstructive jaundice.Methods 100 cases of percutaneous transhepatic catheterizde drainage (PTCD) and percutaneous transhepatic biliary stenting (PTBS) done for advanced malignant obstructive jaundice were divided into control group and experimental group,50 cases in each group.In experimental group,100 mg pethidine hydrochloride and 10 mg anisodamine were injected intramuscularly 30 min before operation,while in control group,no analgesic or antispasmodic were used before and during operation.The blood pressure and heart rate were observed,the incidence rate of biliary-cardiac reflex and operating time were recorded,while the scale of pain felt by patient was evaluated with visual analogue scale.Results Compared to the control group,the patients in experimental group have more stable vital signs,feel more comfortable,suffering shorter operative time,less incidence rate of biliary cardiac reflex and less pain by using pethidine hydrochloride and anisodamine.Conclusion Application of pathidine hydrochloride and anisodamine during the transhepatic biliary drainage and stent implantation done on the patient with advanced malignant obstructive jaundice may release pain,reduce operating time.It is safe,at lower cost and can be used as routine medicine before PTCD or PTBS.
