Treatment of primary hepatic carcinoma by transcatheter artery combined with portal vein chemoembolization
10.3969/j.issn.1002-1671.2017.08.028
- VernacularTitle:经肝动脉同时直接经门静脉联合介入治疗原发性肝癌
- Author:
Kefeng JIA
;
Changlu YU
;
Cheng SUN
;
Yujuan HAN
;
Fengmei WANG
;
Xiang JING
;
Chuanshan ZHANG
- Keywords:
primary hepatic carcinoma;
transarterial arterial chemoembolization;
portal vein chemoembolization;
liver volume
- From:
Journal of Practical Radiology
2017;33(8):1269-1272
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy and postoperative liver function in patients with primary hepatic carcinoma treated by transcatheter arterial chemoembolization(TACE) or TACE combined with portal vein chemoembolization.Methods 48 patients with primary hepatic carcinoma, randomly divided into 2 groups (hepatic artery group in 25 cases and dual interventional group in 23 cases),underwent interventional treatment.The hepatic artery group underwent conventional hepatic artery interventional therapy, while the dual interventional group underwent hepatic artery and portal vein interventional treatment.The postoperative clinical efficiency, liver volume and liver function between the two groups'' patients were compared.Results To the endpoint of observation,the clinical efficacy and tumor reduction degree of dual interventional group were better than that of hepatic artery group.Compared with hepatic artery group, the postoperative ALT, AST and TBIL of dual interventional group were higher on the first and third days.On the seventh and fourteenth days, the statistical difference was not significant.The volume of non-embolization part in dual interventional group was larger than that in preoperative volume to different degrees.The most obvious change of liver volume happened in the 4th weeks after treatment.There was no treatment-related death or severe adverse reaction in two groups.Conclusion The treatment of TACE combined with portal vein chemoembolization is a safe and effective method, which may effectively inhibit the growth and reduce the volume of tumor, and result in compensatory hypertrophy of non-embolization part.
