Exosomes are the pioneer of tumor in surviral advantage
- VernacularTitle:外排体是肿瘤优势生存的开拓者
- Author:
Jiajun CHEN
;
Zhongzu ZHANG
- Keywords:
exosomes;
tumor cells;
metastasis;
immune escape
- From:
Basic & Clinical Medicine
2017;37(8):1190-1194
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are secreted by living cells,which have the lipid bilayer and a large number of inclusions.We have found that exosomes derived from tumor cells play a crucial role in the development of tumor.Tumor-derived exosomes not only act as the messenger between tumor cells,but also perform as a carrier that affects the normal cells far away.Moreover,it has been reported to play positive role in the proliferation,differentiation,metastasis and immune resistance of tumor cells.